The Heart Failure CPX Consortium is a non-funded, non-sponsored collaborative group including the Virginia Commonwealth University, the LeBauer Cardiovascular Research Foundation, Greensboro, the Palo Alto VA Hospital, the University of Milano, San Paolo Hospital, Wake Forest University, and Brigham and Women’s Hospital in Boston, and Stanford University. The collaborators are conducting ongoing studies designed to optimize the application of CPX to predict outcomes in patients with chronic heart failure. In recent years, the group has published studies reinforcing the value of directly measured ventilatory gas exchange responses to exercise in predicting risk in patients with CHF, and demonstrated a primary role of ventilatory efficiency in risk stratification. Additional studies have been published on the many nuances related to CPX, including technical issues, diastolic dysfunction, obesity, pulmonary hypertension, scoring systems, and others. The members of the consortium have contributed to numerous guidelines developed by many of the major organizations.
Selected Papers
Neuromuscular Electrical Stimulation and Inspiratory Muscle Training as Potential Adjunctive Rehabilitation Options for Patients With Heart Failure, Arena, Myers, et al,
Cardiopulmonary exercise testing in patients with pulmonary arterial hypertension, Arena, Myers, et al.
Defining the Optimal Prognostic Window for Cardiopulmonary Exercise Testing in Patients With Heart Failure, Arena, Myers, et al.
Prognostic usefulness of the functional aerobic reserve in patients with heart failure, Chase, Myers, et al,
Cardiopulmonary Exercise Testing: Relevant But Underused, Forman, Myers, et al.
Cardiopulmonary Exercise Testing Variables Reflect the Degree of Diastolic Dysfunction in Patients With Heart Failure, Guazzi, Myers, et al.
Heart Rate Recovery and Tissue Doppler Echocardiography in Heart Failure, Guazzi, Myers, et al.
Determining the Preferred Percent-Predicted Equation for Peak Oxygen Consumption in Patients With Heart Failure, Arena, Myers, et al.
Prognostic Usefulness of Dyspnea Versus Fatigue as Reason for Exercise Test Termination in Patients With Heart Failure, Chase, Myers, et al.
A cardiopulmonary exercise testing score for predicting outcomes in patients with heart failure, Myers, Arena, et al.
The Lowest VE/VCO2 Ratio During Exercise as a Predictor of Outcomes in Patients With Heart Failure, Myers, Arena, et al.
Body Mass, Fitness and Survival in Veteran Patients: Another Obesity Paradox?, McAuley, Myers, et al.
Prognostic value of heart rate recovery in patients with heart failure, Arena, Myers, et al.
Prognostic value of resting end-tidal carbon dioxide in patients with heart failure, Arena, Myers, et al.
The Prognostic Value of Ventilatory Efficiency with Beta-Blocker Therapy in Heart Failure, Arena, Myers, et al, 2005
Cardiopulmonary Exercise Testing in the Clinical and Prognostic Assessment of Diastolic Heart Failure, Guazzi, Myers, et al.
Influence of Heart Failure Etiology on the Prognostic Value of Peak Oxygen Consumption and Minute Ventilation/Carbon Dioxide Production Slope, Arena, Myers, et al.
Peak VO2 and VE/VCO2 slope in patients with heart failure: A prognostic comparison, Arena, Myers, et al.
Exercise Capacity and All-Cause Mortality in African American and Caucasian Men With Type 2 Diabetes, Kokkinos, Myers, et al.
Exercise Capacity and Mortality in Older Men. A 20-Year Follow-Up Study, Kokkinos, Myers et al.
Exercise and Physical Activity: Clinical Outcomes and Applications, Kokkinos, Myers, et al.
Characterizing Differences in Mortality at the Low End of the Fitness Spectrum, Mandic, Myers, et al.
Cardiorespiratory fitness and mortality in diabetic men with 5 and without cardiovascular disease, McAuley, Myers, et al.
Fitness and Fatness as Mortality Predictors in Healthy Older Men, McAuley, Myers, et al.
Obesity Paradox and Cardiorespiratory Fitness in 12,417 Male Veterans aged 40 to 70 years, McAuley, Myers, et al.
Fitness Versus Physical Activity Patterns in Predicting Mortality in Men, Myers, Khayka, et al.
Exercise Capacity and Mortality Among Men Referred for Exercise Testing, Myers, Prakash, et al.